Mechanistic-empirical pavement design guide : features and distinctive elements / دانلود فایل

مشخصات کلی Mechanistic-empirical pavement design guide : features and distinctive elements

نویسنده کتاب (Author):

Martínez Díaz, M.; Pérez Pérez, Ignacio

انتشارات (Publisher):

Escuela de Construcción Civil, Pontificia Universidad Católica de Chile 2015

ویرایش و نوع فایل (Edition/Format):

 Downloadable article : English

منبع (Database):

WorldCat

عنوان ژورنال (Publication):

martinez-diaz-margarita-y-perez-ignacio-mechanistic-empirical-pavement-design-guide-caracteristicas-y-elementos-distintivos-revista-de-la-construccion-online-2015-vol-14-n-1-pp

موضوع (Subject):

Pavement       Design       Management       View all subjects      

توضیحات خلاصه (Summary):

[Abstract] This paper is aimed at describing the most distinctive features of the pavement design method known as Mechanistic-Empirical Pavement Design Guide and to compare it with other renowned methodologies, while emphasizing its advantages and disadvantages. The MEPDG can accurately predict damage evolution, thus helping to choose the most appropriate design for new pavements or to schedule the conservation of the already existing ones. After analyzing different pavement design and management methods, the MEPDG stands out as the most comprehensive one as it takes into account and properly combines the greatest number of factors that affect the pavement. Therefore, some countries outside the USA have already imported and calibrated this method, what, at the same time, allows the scientific community to carry out comparative studies and improve its small deficiencies.[Resumen] El objetivo de este artículo es describir los rasgos más característicos del método de diseño de firmes conocido como Mechanistic-Empirical Pavement Design Guide, así como compararlo con otras metodologías de renombre, destacando sus ventajas y desventajas. El MEPDG puede predecir con precisión la evolución de los deterioros, ayudando por tanto a elegir el diseño más adecuado para el caso de firmes de nueva construcción, o a programar la conservación de los ya existentes. Tras analizar diferentes métodos de diseño y gestión de firmes, el MEPDG destaca como el más completo al ser el que tiene en cuenta un mayor número de factores que afectan al firme. Por ello algunos países fuera de EEUU ya han importado y calibrado este método, lo que al mismo tiempo permite a la comunidad científica llevar a cabo estudios comparativos y mejorar sus pequeñas deficiencias.  Read more…

ژانر / فرم:info:eu-repo/semantics/article

موضوع:Internet resource

نوع منبع:Internet Resource, Article

تمام نویسندگان / همکاران: Martínez Díaz, M.; Pérez Pérez, Ignacio

شناسه OCLC:979265312

Language Note:English

فهرست محتوا:0718-915X http://hdl.handle.net/2183/17742 http://dx.doi.org/10.4067/S0718-915X2015000100004

Parallel construction of wavelet trees on multicore architectures / دانلود فایل

مشخصات کلی Parallel construction of wavelet trees on multicore architectures

نویسنده کتاب (Author):

Fuentes Sepúlveda, José; Elejalde, Erick; Ferres, Leo; Seco, Diego

انتشارات (Publisher):

Springer U K 2016-10-05

ویرایش و نوع فایل (Edition/Format):

 Downloadable article : English

منبع (Database):

WorldCat

عنوان ژورنال (Publication):

fuentes-sepulveda-j-elejalde-e-ferres-l-et-al-knowl-inf-syst-2016-doi10-1007s10115-016-1000-6

موضوع (Subject):

Succinct data structure       Wavelet tree construction       Multicore       View all subjects      

توضیحات خلاصه (Summary):

[Abstract] The wavelet tree has become a very useful data structure to efficiently represent and query large volumes of data in many different domains, from bioinformatics to geographic information systems. One problem with wavelet trees is their construction time. In this paper, we introduce two algorithms that reduce the time complexity of a wavelet tree’s construction by taking advantage of nowadays ubiquitous multicore machines. Our first algorithm constructs all the levels of the wavelet in parallel with O(n) time and O(nlgσ+σlgn)O(nlg⁡σ+σlg⁡n) bits of working space, where n is the size of the input sequence and σσ is the size of the alphabet. Our second algorithm constructs the wavelet tree in a domain decomposition fashion, using our first algorithm in each segment, reaching O(lgn)O(lg⁡n) time and O(nlgσ+pσlgn/lgσ)O(nlg⁡σ+pσlg⁡n/lg⁡σ) bits of extra space, where p is the number of available cores. Both algorithms are practical and report good speedup for large real datasets.  Read more…

ژانر / فرم:info:eu-repo/semantics/article

موضوع:Internet resource

نوع منبع:Internet Resource, Article

تمام نویسندگان / همکاران: Fuentes Sepúlveda, José; Elejalde, Erick; Ferres, Leo; Seco, Diego

شناسه OCLC:979265307

Language Note:English

فهرست محتوا:0219-1377 0219-3116 http://hdl.handle.net/2183/18149 10.1007/s10115-016-1000-6

Abundance and distribution of invertebrate larvae in the Bellingshausen Sea (West Antarctica) / دانلود فایل

مشخصات کلی Abundance and distribution of invertebrate larvae in the Bellingshausen Sea (West Antarctica)

نویسنده کتاب (Author):

Ameneiro, Julia; Mouriño-Carballido, Beatriz; Parapar, Julio; Vázquez, Elsa

انتشارات (Publisher):

Springer 2012

ویرایش و نوع فایل (Edition/Format):

 Downloadable article : English

منبع (Database):

WorldCat

عنوان ژورنال (Publication):

ameneiro-j-mourin%cc%83o-carballido-b-parapar-j-et-al-polar-biol-2012-35-1359-doi10-1007s00300-012-1177-4

موضوع (Subject):

Bellingshausen Sea       Antarctica       Invertebrate larvae       View all subjects      

توضیحات خلاصه (Summary):

The central part of the Bellingshausen Sea has been poorly studied, partly because of the presence of ice during most of the year. The main aim of this study was to analyse the abundance and distribution of meroplankton, and the influence of oceanographic properties were investigated in the Bellingshausen Sea (West Antarctica) during the BENTART-06 cruise carried out in January–February 2006. Zooplankton samples were collected with a 80-μm mesh plankton net hauled vertically from a depth of 200 m to the surface at fifteen stations across the Bellingshausen Sea. Fifteen types of larval benthic invertebrates were found, with echinospira and nudibranch veligers being the most abundant. Hierarchical analysis and non-metric multidimensional scaling revealed a high degree of spatial variability in both larval abundance and larval types across the Bellingshausen Sea. The variability was significantly correlated with total chlorophyll-a and the contribution of large (>5 μm) phytoplankton to total chlorophyll, indicating the availability of food as an important factor determining the larval distribution observed. Nudibranch veligers, nemertean pilidia, echinoderm and planula larvae were more abundant at stations in the central Bellingshausen Sea, which was characterized by low phytoplankton biomass and production. Higher abundances of echinospira veligers and polychaete larvae were found at the more productive stations close to Peter I Island and the Antarctic Peninsula. The abundance and diversity of larval types found in the Bellingshausen Sea during the BENTART-06 cruise support the hypothesis that indirect development through larval swimming stages plays a key role in benthic recruitment in polar areas.  Read more…

ژانر / فرم:info:eu-repo/semantics/article

موضوع:Internet resource

نوع منبع:Internet Resource, Article

تمام نویسندگان / همکاران: Ameneiro, Julia; Mouriño-Carballido, Beatriz; Parapar, Julio; Vázquez, Elsa

شناسه OCLC:979265304

Language Note:English

فهرست محتوا:1432-2056 http://hdl.handle.net/2183/17643

Microemulsions for colorectal cancer treatments: general considerations and formulation of methotrexate / دانلود فایل

مشخصات کلی Microemulsions for colorectal cancer treatments: general considerations and formulation of methotrexate

نویسنده کتاب (Author):

Flores, Sergio E.; Rial-Hermida, M.Isabel; Ramírez, Jorge C.; Pazos, A.; Concheiro, Ángel; Álvarez-Lorenzo, Carmen; Peralta, René D.

انتشارات (Publisher):

Bentham 2016-04-01

ویرایش و نوع فایل (Edition/Format):

 Downloadable article : English

منبع (Database):

WorldCat

عنوان ژورنال (Publication):

flores-se-rial-hermida-mi-ramirez-jc-et-al-microemulsions-for-colorectal-cancer-treatments-general-considerations-and-formulation-of-methotrexate-mini-rev-med-chem-2016166498-508

موضوع (Subject):

Antitumor therapy       Colorectal cancer       Essential oils       View all subjects      

توضیحات خلاصه (Summary):

[Abstract] Microemulsions combine the advantages of emulsions with those of nanocarriers, overcoming the stability problems of the former and providing facile scalable systems with compartments adequate for high drug loadings. Recently, microemulsions are gaining attention in the formulation of anticancer drugs not only for topical treatment, but also for systemic delivery as well as for the development of theranostic systems. The aim of this paper is two-fold. First, an updated review about general features, preparation, characterization and pharmaceutical applications, with a special focus on colorectal cancer, is provided. Second, a case study of formulation of methotrexate in microemulsions is presented. Various essential oils (menthol, trans-anethole, α-tocopherol) and surfactants (TPGS-l000, Maxemul 6112, Noigen RN-20) were investigated for the preparation of o/w microemulsions for the delivery of methotrexate, and the ability of methotrexate-loaded microemulsions to inhibit cancer cell growth was then evaluated. Disregarding the surfactants used, menthol and trans-anethole led to cytotoxic microemulsions, whereas α-tocopherol based-formulations induced cell proliferation. These findings highlight the role that the oily component may play in the efficacy and safety of the microemulsions.  Read more…

ژانر / فرم:info:eu-repo/semantics/article

موضوع:Internet resource

نوع منبع:Internet Resource, Article

تمام نویسندگان / همکاران: Flores, Sergio E.; Rial-Hermida, M.Isabel; Ramírez, Jorge C.; Pazos, A.; Concheiro, Ángel; Álvarez-Lorenzo, Carmen; Peralta, René D.

شناسه OCLC:979265301

Language Note:English

فهرست محتوا:http://hdl.handle.net/2183/17508

Identification of the main driving mechanisms in the evolution of a small coastal wetland (Traba, Galicia, NW Spain) since its origin 5700 cal yr BP / دانلود فایل

مشخصات کلی Identification of the main driving mechanisms in the evolution of a small coastal wetland (Traba, Galicia, NW Spain) since its origin 5700 cal yr BP

نویسنده کتاب (Author):

Bao, Roberto; Alonso, Ángela; Delgado, Cristina; Pagés, Jose Luis

انتشارات (Publisher):

Elsevier 2007

ویرایش و نوع فایل (Edition/Format):

 Downloadable article : English

منبع (Database):

WorldCat

عنوان ژورنال (Publication):

bao-r-alonso-a-delgado-c-pages-j-l-2007-identification-of-the-main-driving-mechanisms-in-the-evolution-of-a-small-coastal-wetland-traba-galicia-nw-spain-since-its-origin-5700-ca

موضوع (Subject):

Coastal evolution       Coastal palaeoenvironments       Sea-level change       View all subjects      

توضیحات خلاصه (Summary):

This paper examines the interdependence among the different forcing factors in the evolution of the Traba coastal wetland (Galicia, NW Spain) based on lithofacies and diatom analyses of three cores reaching the basement. According to radiocarbon data, the wetland originated 5700 cal yr BP, a time when similar systems on the Atlantic coast of the Iberian Peninsula were formed. Diatom assemblage data allow the estimation of the sea level position at 5700 cal yr BP at least 7 m below present-day mean sea level. Attenuation of the sea-level rise at that time was a major driving mechanism that permitted the establishment of an incipient beach–dune complex, causing water-logging in the Traba basin. However, the location of this incipient wetland on a basement high, which prevented an open connection to the sea, made topographic inheritance the main forcing factor in the subsequent evolution of the wetland. Thus, Traba was never a coastal lagoon system, as it has sometimes been defined. The maximum permeability of the beach–dune complex enclosing the wetland was recorded after its origin until 2900 cal yr BP, when increased stormy conditions affected the Galician shelf waters. Since then, the evolution of the wetland has been mainly controlled by more local factors, especially the continental sediment supply. Changes in land use in the basin have accelerated the infilling of the water body since the 19th century. This rapid infilling makes the whole system more prone to total encroachment in the short term, rather than to sea drowning. Palaeoenvironmental analyses showing the main trends in the long-term evolution of coastal wetlands can be of key importance in any management decisions aimed at preserving these kinds of sensitive coastal environments.  Read more…

ژانر / فرم:info:eu-repo/semantics/article

موضوع:Internet resource

نوع منبع:Internet Resource, Article

تمام نویسندگان / همکاران: Bao, Roberto; Alonso, Ángela; Delgado, Cristina; Pagés, Jose Luis

شناسه OCLC:979265265

Language Note:English

فهرست محتوا:0031-0182 http://hdl.handle.net/2183/18269

Effects of degree of urbanization and lifetime longest-held occupation on cognitive impairment prevalence in an older spanish population / دانلود فایل

مشخصات کلی Effects of degree of urbanization and lifetime longest-held occupation on cognitive impairment prevalence in an older spanish population

نویسنده کتاب (Author):

Lorenzo-López, Laura; Millán-Calenti, José Carlos; López-López, Rocío; Diego-Díez, Clara; Laffon, Blanca; Pásaro, Eduardo; Valdiglesias, Vanessa; Maseda, Ana

انتشارات (Publisher):

Frontiers 2017-02-13

ویرایش و نوع فایل (Edition/Format):

 Downloadable article : English

منبع (Database):

WorldCat

عنوان ژورنال (Publication):

lorenzo-lopez-l-millan-calenti-jc-lopez-lopez-r-et-al-effects-of-degree-of-urbanization-and-lifetime-longest-held-occupation-on-cognitive-impairment-prevalence-in-an-older

موضوع (Subject):

Urbanization       Rurality       Occupation       View all subjects      

توضیحات خلاصه (Summary):

[Abstract] Our aim was to estimate the prevalence of cognitive impairment in rural and urban elderly populations and to examine the relationship between lifetime occupation and general cognitive performance. A cross-sectional study was carried out covering a representative sample (n = 749) of adults aged ≥65 years. Two categories were created to define the degree of urbanization using a criterion of geographical contiguity in combination with a minimum population threshold: densely populated (urban) areas and intermediate-thinly populated (rural) areas. Occupational histories were ranked by skill level requirements according to the Spanish National Classification of Occupations. Prevalence estimates of cognitive impairment were measured with the Mini-Mental State Examination. Results show that rural residence was not significantly associated with higher risk of cognitive impairment. A protective effect of cognitive demands at work against age-related cognitive decline was observed. However, this effect was not independent of confounder factors, such as age and education. A low overall prevalence of cognitive impairment was observed (6.5%), compared with previous estimates, possibly due to the sample selection in senior centers. Occupation during active life is not an isolated protective factor against cognitive impairment, and it is closely related to educational level. In future geriatric programs, description of both factors should be taken into consideration in screening older adults at increased risk of cognitive impairment and dementia.  Read more…

ژانر / فرم:info:eu-repo/semantics/article

موضوع:Internet resource

نوع منبع:Internet Resource, Article

تمام نویسندگان / همکاران: Lorenzo-López, Laura; Millán-Calenti, José Carlos; López-López, Rocío; Diego-Díez, Clara; Laffon, Blanca; Pásaro, Eduardo; Valdiglesias, Vanessa; Maseda, Ana

شناسه OCLC:979265264

Language Note:English

فهرست محتوا:1664-1078 http://hdl.handle.net/2183/18275

A generalized NEG wage-type equation / دانلود فایل

مشخصات کلی A generalized NEG wage-type equation

نویسنده کتاب (Author):

Bruna, Fernando

انتشارات (Publisher):

Cambridge Scholars Publishing 2015-10-01

ویرایش و نوع فایل (Edition/Format):

 Downloadable article : English

منبع (Database):

WorldCat

عنوان ژورنال (Publication):

bruna-f-2015-a-generalized-neg-wage-type-equation-in-diaz-roldan-c-and-perote-j-eds-advances-on-international-economics-chapter-4-pp-63-82-cambridge-scholars-publishing

موضوع (Subject):

New Economic Geography       NEG       Wage equation       View all subjects      

توضیحات خلاصه (Summary):

[Abstract]: This chapter discusses several controversial issues of the New Economic Geography (NEG) theory, focusing on some problems of interpretation regarding the estimation results of a wage equation. In order to do that, several wage equations found in the literature are encompassed under the derivation of a new generalized wage-type equation, with marginal cost as dependent variable. A testable equation controlling for human and physical capital stocks is also derived.  Read more…

ژانر / فرم:info:eu-repo/semantics/bookPart

موضوع:Internet resource

نوع منبع:Internet Resource, Article

تمام نویسندگان / همکاران: Bruna, Fernando

شناسه OCLC:979265255

Language Note:English

فهرست محتوا:97-8144384-616-5 http://hdl.handle.net/2183/18238

Algunas notas sobre el comportamiento de las zahorras en los firmes / دانلود فایل

مشخصات کلی Algunas notas sobre el comportamiento de las zahorras en los firmes

نویسنده کتاب (Author):

Romana García, Manuel; Pérez Pérez, Ignacio; Navarro Gamir, Vicente

انتشارات (Publisher):

Entorno Gráfico 2000

ویرایش و نوع فایل (Edition/Format):

 Downloadable article : Spanish

منبع (Database):

WorldCat

عنوان ژورنال (Publication):

romana-garcia-m-perez-perez-i-navarro-gamir-v-2000-algunas-notas-sobre-el-comportamiento-de-las-zahorras-en-los-firmes-ingeopres-82-pp-18-22-issn-1136-4785

موضوع (Subject):

Riesgos de imprimación       Riscos de imprimación       Zahorras       View all subjects      

توضیحات خلاصه (Summary):

[Resumen:] Al hilo de lo discutido en el reciente V Congreso Nacional de Firmes, sobre las capas de base de los firmes, en este artículo se exponen las misiones de las bases granulares en cada tipo de firme, con algunas notas de la importancia de los riegos de imprimación y de evitar la segregación, como principal enemigo de la respuesta de estos materiales a lo largo de su vida. Finalmente, se exponen algunas conclusiones que resumen estas misiones, y combaten algunas concepciones falsas que pueden escucharse en algunas ocasiones.  Read more…

ژانر / فرم:info:eu-repo/semantics/article

موضوع:Internet resource

نوع منبع:Internet Resource, Article

تمام نویسندگان / همکاران: Romana García, Manuel; Pérez Pérez, Ignacio; Navarro Gamir, Vicente

شناسه OCLC:979265250

Language Note:Spanish

فهرست محتوا:1136-4785 http://hdl.handle.net/2183/18203

Prospective evaluation of testing with baked milk to predict safe ingestion of baked milk in unheated milk-allergic children / دانلود فایل

مشخصات کلی Prospective evaluation of testing with baked milk to predict safe ingestion of baked milk in unheated milk-allergic children

نویسنده کتاب (Author):

Kwan, Allison; Asper, Maria; Lavi, Sasson; Lavine, Elana; Hummel, David; Upton, Julia

انتشارات (Publisher):

BioMed Central Ltd. 2016-10-24

ویرایش و نوع فایل (Edition/Format):

 Downloadable article : English

منبع (Database):

WorldCat

عنوان ژورنال (Publication):

BioMed Central Ltd.

موضوع (Subject):

Cow’s milk allergy, Baked milk, Skin prick testing      

توضیحات خلاصه (Summary):

Abstract Background Cow’s milk allergy is one of the most common food allergies affecting young children. A subset of milk-allergic individuals can eat baked milk without allergic symptoms which is beneficial in terms of prognostication and liberalization of the diet. A retrospective study suggested that skin prick testing (SPT) with a baked milk (muffin) slurry may provide a sensitive means of predicting the outcome of a medically supervised baked milk oral food challenge. We evaluated the predictive value of SPT with baked milk to identify unheated milk-allergic children who are able to safely eat baked milk. Methods Children aged 2–16 years with a prior history of reaction to milk and a milk extract SPT of 8–14 mm were recruited. Investigator-blinded SPT to muffin slurry and powdered milk in triplicate and specific IgE (sIgE) to casein and milk were performed. Graded oral challenge to egg-free baked milk muffins (total 2.6 gm milk protein) was performed in the hospital. Reliability of tests was analyzed for intraclass correlation. Statistical significance for clinical characteristics of population and muffin testing versus baked milk reactivity was calculated with Fisher exact test for dichotomous and t-test for continuous variables. Wilcoxon rank sum test was used to compare immunological characteristics between individuals who tolerated or reacted to baked milk. Fitted predicted probability curves and ROC curves were generated. Results Thirty-eight children were consented and 30 met study criteria. The muffin SPT and casein sIgE were significantly different in those who passed versus failed baked milk challenge. Negative (<3 mm) baked milk tests were found in 8/30 children (27 %) and were associated with non-reactivity to baked milk (p = 0.01) with a sensitivity of 1 (0.70–1.00). All children with negative SPT for baked milk passed the oral challenge. Specificity was 0.41 (0.19–0.67). The optimal decision point for the muffin SPT was 4 mm and the casein sIgE wa  Read more…

ژانر / فرم:Research

موضوع:Internet resource

نوع منبع:Internet Resource, Article

تمام نویسندگان / همکاران: Kwan, Allison; Asper, Maria; Lavi, Sasson; Lavine, Elana; Hummel, David; Upton, Julia

شناسه OCLC:979265213

Language Note:English