مشخصات کلی MI-NODES multiscale models of metabolic reactions, brain connectome, ecological, epidemic, world trade, and legal-social networks
نویسنده کتاب (Author):
Duardo-Sánchez, Aliuska; González-Díaz, Humberto; Pazos, A.
انتشارات (Publisher):
ویرایش و نوع فایل (Edition/Format):
Downloadable article : English
منبع (Database):
عنوان ژورنال (Publication):
duardo-sanchez-a-gonzalez-diaz-h-pazos-a-mi-nodes-multiscale-models-of-metabolic-reactions-brain-connectome-ecological-epidemic-world-trade-and-legal-social-networks-curr-bi
موضوع (Subject):
QSPR models in complex networks Drug-target networks Metabolic networks View all subjects
توضیحات خلاصه (Summary):
[Abstract] Complex systems and networks appear in almost all areas of reality. We find then from proteins residue networks to Protein Interaction Networks (PINs). Chemical reactions form Metabolic Reactions Networks (MRNs) in living beings or Atmospheric reaction networks in planets and moons. Network of neurons appear in the worm C. elegans, in Human brain connectome, or in Artificial Neural Networks (ANNs). Infection spreading networks exist for contagious outbreaks networks in humans and in malware epidemiology for infection with viral software in internet or wireless networks. Social-legal networks with different rules evolved from swarm intelligence, to hunter-gathered societies, or citation networks of U.S. Supreme Court. In all these cases, we can see the same question. Can we predict the links based on structural information? We propose to solve the problem using Quantitative Structure-Property Relationship (QSPR) techniques commonly used in chemo-informatics. In so doing, we need software able to transform all types of networks/graphs like drug structure, drug-target interactions, protein structure, protein interactions, metabolic reactions, brain connectome, or social networks into numerical parameters. Consequently, we need to process in alignment-free mode multitarget, multiscale, and multiplexing, information. Later, we have to seek the QSPR model with Machine Learning techniques. MI-NODES is this type of software. Here we review the evolution of the software from chemoinformatics to bioinformatics and systems biology. This is an effort to develop a universal tool to study structure-property relationships in complex systems. Read more…
ژانر / فرم:info:eu-repo/semantics/article
موضوع:Internet resource
نوع منبع:Internet Resource, Article
تمام نویسندگان / همکاران: Duardo-Sánchez, Aliuska; González-Díaz, Humberto; Pazos, A.
شناسه OCLC:979265311
Language Note:English
فهرست محتوا:2212-392X 1574-8936 http://hdl.handle.net/2183/17634
